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Clinical Protocols

National Guidelines for Rabies Prophylaxis

Standardized evidence-based consensus guidelines developed by the Consortium Against Rabies adhering to WHO expert consultation standards.

The Golden Rule: Immediate First Aid Saves Lives

Immediate vigorous washing of all animal bite wounds and scratches with running tap water and soap for at least 15 minutes physically removes up to 90% of the viral inoculate. This single measure drastically reduces rabies transmission risk.

Wash thoroughly with soap & water Apply povidone iodine or alcohol antiseptic DO NOT suture wounds immediately DO NOT apply lime, chili, oil or mud

Risk Assessment & Category Triage

Category I

Touching or Feeding Animals

Touching, feeding suspected animals, or licks on intact skin without open wounds.

Required Action:

Wash exposed skin surfaces. No vaccine or immunoglobulin required if history is reliable.

Category II

Minor Scratches / Nibbling

Nibbling of uncovered skin, minor scratches or abrasions without bleeding.

Required Action:

Immediate wound washing + Complete Anti-Rabies Vaccine (ARV) course. RIG is not routinely required unless immunocompromised.

Category III

Transdermal Bites / Bleeding

Single or multiple transdermal bites or scratches, licks on broken skin, contamination of mucous membranes.

Required Action:

Immediate washing + Full Anti-Rabies Vaccine course + Rabies Immunoglobulin (RIG) thoroughly infiltrated into all wounds.

Clinical Update

Intradermal Rabies Vaccination (IDRV)

CAR has been at the forefront of popularizing the Intradermal Route in India. Instead of using 1 full vial (0.5ml or 1.0ml) per visit via intramuscular route, the intradermal route uses just 0.1 ml per site.

  • Up to 80% Cost Reduction: Allows 1 vaccine vial to treat multiple bite patients.
  • Identical Seroconversion: Triggers equivalent or superior protective neutralising antibodies.
  • Updated 2-Site Schedule: 2 sites (0.1 ml each deltoid) on Days 0, 3, and 7.

Rabies Immunoglobulin (RIG) Dosages

Equine Rabies Immunoglobulin (ERIG)40 IU / kg body wt

Skin sensitivity testing is no longer mandated by WHO guidelines; have adrenaline on standby.

Human Rabies Immunoglobulin (HRIG)20 IU / kg body wt

As much of the calculated dose as anatomically feasible should be infiltrated locally into and around the wound(s).

Download Official Protocols & CMEs

WHO Rabies Position Paper (PDF)PEP Algorithm Wall Chart (PNG)View All CME Lectures & Booklets →